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Budesonide, but not dexamethasone, blunted the response of aldosterone to renin elevation by suppressing angiotensin converting enzyme upon high-altitude exposure

INTRODUCTION: Inhaled budesonide is a novel approach to prevent acute mountain sickness (AMS). However, its mechanism is not completely understood. We aimed to investigate the effects of budesonide and dexamethasone on renin–angiotensin–aldosterone system in AMS prevention. MATERIALS AND METHODS: Da...

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Detalles Bibliográficos
Autores principales: Li, Hui-Jie, Zheng, Cheng-Rong, Chen, Guo-Zhu, Qin, Jun, Zhang, Ji-Hang, Yu, Jie, Zhang, En-Hao, Huang, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843924/
https://www.ncbi.nlm.nih.gov/pubmed/27317302
http://dx.doi.org/10.1177/1470320316653867