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Cellular prion protein and γ-synuclein overexpression in LS 174T colorectal cancer cell drives endothelial proliferation-to-differentiation switch

BACKGROUND: Tumor-induced angiogenesis is an imperative event in pledging new vasculature for tumor metastasis. Since overexpression of neuronal proteins gamma-synuclein (γ-Syn) and cellular prion protein (PrP(C)) is always detected in advanced stages of cancer diseases which involve metastasis, thi...

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Detalles Bibliográficos
Autores principales: Ong, Sing-Hui, Goh, Kai-Wey, Chieng, Cornelius Kwang-Lee, Say, Yee-How
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844251/
https://www.ncbi.nlm.nih.gov/pubmed/29527422
http://dx.doi.org/10.7717/peerj.4506