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Whole-Genome Sequence Accuracy Is Improved by Replication in a Population of Mutagenized Sorghum

The accurate detection of induced mutations is critical for both forward and reverse genetics studies. Experimental chemical mutagenesis induces relatively few single base changes per individual. In a complex eukaryotic genome, false positive detection of mutations can occur at or above this mutagen...

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Detalles Bibliográficos
Autores principales: Addo-Quaye, Charles, Tuinstra, Mitch, Carraro, Nicola, Weil, Clifford, Dilkes, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844295/
https://www.ncbi.nlm.nih.gov/pubmed/29378822
http://dx.doi.org/10.1534/g3.117.300301