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Unintended Side Effects of Transformation Are Very Rare in Cryptococcus neoformans

Received wisdom in the field of fungal biology holds that the process of editing a genome by transformation and homologous recombination is inherently mutagenic. However, that belief is based on circumstantial evidence. We provide the first direct measurement of the effects of transformation on a fu...

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Detalles Bibliográficos
Autores principales: Friedman, Ryan Z., Gish, Stacey R., Brown, Holly, Brier, Lindsey, Howard, Nicole, Doering, Tamara L., Brent, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844303/
https://www.ncbi.nlm.nih.gov/pubmed/29305388
http://dx.doi.org/10.1534/g3.117.300357