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Comparison of Various Nuclear Localization Signal-Fused Cas9 Proteins and Cas9 mRNA for Genome Editing in Zebrafish

The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system has been proven to be an efficient and precise genome editing technology in various organisms. However, the gene editing efficiencies of Cas9 proteins with a nuclear localization signal (NLS) fused to different termin...

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Detalles Bibliográficos
Autores principales: Hu, Peinan, Zhao, Xueying, Zhang, Qinghua, Li, Weiming, Zu, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844304/
https://www.ncbi.nlm.nih.gov/pubmed/29295818
http://dx.doi.org/10.1534/g3.117.300359