Genomic Identification and Functional Characterization of Essential Genes in Caenorhabditis elegans

Using combined genetic mapping, Illumina sequencing, bioinformatics analyses, and experimental validation, we identified 60 essential genes from 104 lethal mutations in two genomic regions of Caenorhabditis elegans totaling ∼14 Mb on chromosome III(mid) and chromosome V(left). Five of the 60 genes h...

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Detalles Bibliográficos
Autores principales: Qin, Zhaozhao, Johnsen, Robert, Yu, Shicheng, Chu, Jeffrey Shih-Chieh, Baillie, David L., Chen, Nansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844317/
https://www.ncbi.nlm.nih.gov/pubmed/29339407
http://dx.doi.org/10.1534/g3.117.300338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844317/
https://www.ncbi.nlm.nih.gov/pubmed/29339407
http://dx.doi.org/10.1534/g3.117.300338

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