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Genomic Identification and Functional Characterization of Essential Genes in Caenorhabditis elegans
Using combined genetic mapping, Illumina sequencing, bioinformatics analyses, and experimental validation, we identified 60 essential genes from 104 lethal mutations in two genomic regions of Caenorhabditis elegans totaling ∼14 Mb on chromosome III(mid) and chromosome V(left). Five of the 60 genes h...
Autores principales: | Qin, Zhaozhao, Johnsen, Robert, Yu, Shicheng, Chu, Jeffrey Shih-Chieh, Baillie, David L., Chen, Nansheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844317/ https://www.ncbi.nlm.nih.gov/pubmed/29339407 http://dx.doi.org/10.1534/g3.117.300338 |
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