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Carboplatin dose based on actual renal function: no excess of acute haematotoxicity in adjuvant treatment in seminoma stage I

INTRODUCTION: The practice of carboplatin dosing is not concordant among different centres and oncologists. Some clinical guidelines recommend capping of the carboplatin dose at, for example, creatinine-clearance (Crea-Cl) of 125 mL/min because of concerns of excessive toxicity. Clinical data to sup...

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Detalles Bibliográficos
Autores principales: Fehr, Martin, Maranta, Angela Fischer, Reichegger, Hermann, Gillessen, Silke, Cathomas, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844370/
https://www.ncbi.nlm.nih.gov/pubmed/29531843
http://dx.doi.org/10.1136/esmoopen-2018-000320