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Carboplatin dose based on actual renal function: no excess of acute haematotoxicity in adjuvant treatment in seminoma stage I
INTRODUCTION: The practice of carboplatin dosing is not concordant among different centres and oncologists. Some clinical guidelines recommend capping of the carboplatin dose at, for example, creatinine-clearance (Crea-Cl) of 125 mL/min because of concerns of excessive toxicity. Clinical data to sup...
Autores principales: | Fehr, Martin, Maranta, Angela Fischer, Reichegger, Hermann, Gillessen, Silke, Cathomas, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844370/ https://www.ncbi.nlm.nih.gov/pubmed/29531843 http://dx.doi.org/10.1136/esmoopen-2018-000320 |
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