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Facilitated sequence assembly using densely labeled optical DNA barcodes: A combinatorial auction approach
The output from whole genome sequencing is a set of contigs, i.e. short non-overlapping DNA sequences (sizes 1-100 kilobasepairs). Piecing the contigs together is an especially difficult task for previously unsequenced DNA, and may not be feasible due to factors such as the lack of sufficient covera...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844556/ https://www.ncbi.nlm.nih.gov/pubmed/29522539 http://dx.doi.org/10.1371/journal.pone.0193900 |