Yeast-based assays for characterization of the functional effects of single nucleotide polymorphisms in human DNA repair genes

DNA repair mechanisms maintain genomic integrity upon exposure to various types of DNA damage, which cause either single- or double-strand breaks in the DNA. Here, we propose a strategy for the functional study of single nucleotide polymorphisms (SNPs) in the human DNA repair genes XPD/ERCC2, RAD18,...

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Detalles Bibliográficos
Autores principales: Kim, Changshin, Yang, Jinmo, Jeong, Su-Hyun, Kim, Hayoung, Park, Geun-hee, Shin, Hwa Beom, Ro, MyungJa, Kim, Kyoung-Yeon, Park, YoungJoon, Kim, Keun Pil, Kwack, KyuBum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844570/
https://www.ncbi.nlm.nih.gov/pubmed/29522548
http://dx.doi.org/10.1371/journal.pone.0193823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844570/
https://www.ncbi.nlm.nih.gov/pubmed/29522548
http://dx.doi.org/10.1371/journal.pone.0193823

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