Genetic Polymorphism of Thiopurine S-methyltransferase in Children with Acute Lymphoblastic Leukemia in Jordan

BACKGROUND AND AIMS: It has been demonstrated that homozygote and heterozygote mutant allele carriers for thiopurine S-methyltransferase (TPMT) are at high risk of developing myelosuppression after receiving standard doses of 6-mercaptopurine (6-MP). The aim of this study was to determine the freque...

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Detalles Bibliográficos
Autores principales: Alsous, Mervat, Yousef, Al-Motassem, Jalil, Mariam Abdel, Zawiah, Mohammed, Yacoub, Shorouq, Momani, Deema, Gharabli, Alia, Omar, Suha, Rihani, Rawad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844618/
https://www.ncbi.nlm.nih.gov/pubmed/29373914
http://dx.doi.org/10.22034/APJCP.2018.19.1.199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844618/
https://www.ncbi.nlm.nih.gov/pubmed/29373914
http://dx.doi.org/10.22034/APJCP.2018.19.1.199

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