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Curcumin Analog Pentagamavunon-1 (PGV-1) Sensitizes Widr Cells to 5-Fluorouracil through Inhibition of NF-κB Activation

Cell cycle regulation and the NF-κB pathway in cancer cells are important in mediating resistance to 5-Fluorouracil (5-FU). Pentagamavunon-1 (PGV-1), a curcumin analog, is known to exhibit stronger growth inhibitory effects than curcumin itself in several cancer cells. In this study, we evaluated th...

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Detalles Bibliográficos
Autores principales: Meiyanto, Edy, Septisetyani, Endah Puji, Larasati, Yonika Arum, Kawaichi, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844636/
https://www.ncbi.nlm.nih.gov/pubmed/29373892
http://dx.doi.org/10.22034/APJCP.2018.19.1.49