Cargando…
Curcumin Analog Pentagamavunon-1 (PGV-1) Sensitizes Widr Cells to 5-Fluorouracil through Inhibition of NF-κB Activation
Cell cycle regulation and the NF-κB pathway in cancer cells are important in mediating resistance to 5-Fluorouracil (5-FU). Pentagamavunon-1 (PGV-1), a curcumin analog, is known to exhibit stronger growth inhibitory effects than curcumin itself in several cancer cells. In this study, we evaluated th...
Autores principales: | Meiyanto, Edy, Septisetyani, Endah Puji, Larasati, Yonika Arum, Kawaichi, Masashi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
West Asia Organization for Cancer Prevention
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844636/ https://www.ncbi.nlm.nih.gov/pubmed/29373892 http://dx.doi.org/10.22034/APJCP.2018.19.1.49 |
Ejemplares similares
-
Anti-proliferative and Anti-metastatic Potential of Curcumin Analogue, Pentagamavunon-1 (PGV-1), Toward Highly Metastatic Breast Cancer Cells in Correlation with ROS Generation
por: Meiyanto, Edy, et al.
Publicado: (2019) -
Systematic analysis of potential targets of the curcumin analog pentagamavunon-1 (PGV-1) in overcoming resistance of glioblastoma cells to bevacizumab
por: Hermawan, Adam, et al.
Publicado: (2021) -
Pentagamavunon-1 (PGV-1) inhibits ROS metabolic enzymes and suppresses tumor cell growth by inducing M phase (prometaphase) arrest and cell senescence
por: Lestari, Beni, et al.
Publicado: (2019) -
The Chemopreventive Activity of Indonesia Medicinal Plants Targeting on Hallmarks of Cancer
por: Meiyanto, Edy, et al.
Publicado: (2019) -
Preparation and Cytotoxic Evaluation of PGV-1 Derivative, CCA-1.1, as a New Curcumin Analog with Improved-Physicochemical and Pharmacological Properties
por: Utomo, Rohmad Yudi, et al.
Publicado: (2022)