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ZFP226 is a novel artificial transcription factor for selective activation of tumor suppressor KIBRA

KIBRA has been suggested as a key regulator of the hippo pathway, regulating organ size, cell contact inhibition as well as tissue regeneration and tumorigenesis. Recently, alterations of KIBRA expression caused by promotor methylation have been reported for several types of cancer. Our current stud...

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Detalles Bibliográficos
Autores principales: Schelleckes, Katrin, Schmitz, Boris, Lenders, Malte, Mewes, Mirja, Brand, Stefan-Martin, Brand, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844865/
https://www.ncbi.nlm.nih.gov/pubmed/29523820
http://dx.doi.org/10.1038/s41598-018-22600-6