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ZFP226 is a novel artificial transcription factor for selective activation of tumor suppressor KIBRA
KIBRA has been suggested as a key regulator of the hippo pathway, regulating organ size, cell contact inhibition as well as tissue regeneration and tumorigenesis. Recently, alterations of KIBRA expression caused by promotor methylation have been reported for several types of cancer. Our current stud...
Autores principales: | Schelleckes, Katrin, Schmitz, Boris, Lenders, Malte, Mewes, Mirja, Brand, Stefan-Martin, Brand, Eva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844865/ https://www.ncbi.nlm.nih.gov/pubmed/29523820 http://dx.doi.org/10.1038/s41598-018-22600-6 |
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