A simple and robust real-time qPCR method for the detection of PIK3CA mutations

PIK3CA mutations are seemingly the most common driver mutations in breast cancer with H1047R and E545K being the most common of these, accounting together for around 60% of all PIK3CA mutations and have promising therapeutic implications. Given the low sensitivity and the high cost of current genoty...

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Detalles Bibliográficos
Autores principales: Alvarez-Garcia, Virginia, Bartos, Clare, Keraite, Ieva, Trivedi, Urmi, Brennan, Paul M., Kersaudy-Kerhoas, Maïwenn, Gharbi, Karim, Oikonomidou, Olga, Leslie, Nicholas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844869/
https://www.ncbi.nlm.nih.gov/pubmed/29523855
http://dx.doi.org/10.1038/s41598-018-22473-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844869/
https://www.ncbi.nlm.nih.gov/pubmed/29523855
http://dx.doi.org/10.1038/s41598-018-22473-9

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