NF-κB is weakly activated in the NOD mouse model of type 1 diabetes

Type 1 diabetes is an autoimmune disease characterised by selective destruction of pancreatic beta cells by the immune system. The transcription factor nuclear factor-kappa B (NF-κB) regulates innate and adaptive immune responses. Using gene targeting and in vitro analysis of pancreatic islets and i...

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Detalles Bibliográficos
Autores principales: Irvin, Allison E., Jhala, Gaurang, Zhao, Yuxing, Blackwell, Timothy S., Krishnamurthy, Balasubramanian, Thomas, Helen E., Kay, Thomas W. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844878/
https://www.ncbi.nlm.nih.gov/pubmed/29523846
http://dx.doi.org/10.1038/s41598-018-22738-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844878/
https://www.ncbi.nlm.nih.gov/pubmed/29523846
http://dx.doi.org/10.1038/s41598-018-22738-3

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