A Novel Role of Irbesartan in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats: Targeting DDAH/ADMA and EGFR/ERK Signaling

The advent of angiotensin II type 1 receptor blockers (ARBs) as intriguing gastroprotective candidates and the superior pharmacokinetics and pharmacodynamics displayed by irbesartan compared to many other ARBs raised the interest to investigate its gastroprotective potential in a rat model of gastri...

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Detalles Bibliográficos
Autores principales: Shahin, Nancy N., Abdelkader, Noha F., Safar, Marwa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844881/
https://www.ncbi.nlm.nih.gov/pubmed/29523851
http://dx.doi.org/10.1038/s41598-018-22727-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844881/
https://www.ncbi.nlm.nih.gov/pubmed/29523851
http://dx.doi.org/10.1038/s41598-018-22727-6

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