Interferon-β deficiency at asthma exacerbation promotes MLKL mediated necroptosis

Defective production of antiviral interferon (IFN)-β is thought to contribute to rhinovirus-induced asthma exacerbations. These exacerbations are associated with elevated lung levels of lactate dehydrogenase (LDH), indicating occurrence of cell necrosis. We thus hypothesized that reduced lung IFN-β...

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Detalles Bibliográficos
Autores principales: Cerps, Samuel C., Menzel, Mandy, Mahmutovic Persson, Irma, Bjermer, Leif, Akbarshahi, Hamid, Uller, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844912/
https://www.ncbi.nlm.nih.gov/pubmed/29523863
http://dx.doi.org/10.1038/s41598-018-22557-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844912/
https://www.ncbi.nlm.nih.gov/pubmed/29523863
http://dx.doi.org/10.1038/s41598-018-22557-6

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