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Repurposing Auranofin, Ebselen, and PX-12 as Antimicrobial Agents Targeting the Thioredoxin System

As microbial resistance to drugs continues to rise at an alarming rate, finding new ways to combat pathogens is an issue of utmost importance. Development of novel and specific antimicrobial drugs is a time-consuming and expensive process. However, the re-purposing of previously tested and/or approv...

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Detalles Bibliográficos
Autores principales: May, Holly C., Yu, Jieh-Juen, Guentzel, M. N., Chambers, James P., Cap, Andrew P., Arulanandam, Bernard P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844926/
https://www.ncbi.nlm.nih.gov/pubmed/29556223
http://dx.doi.org/10.3389/fmicb.2018.00336