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Development and Application of High-Content Biological Screening for Modulators of NET Production

Neutrophil extracellular traps (NETs) are DNA-based antimicrobial web-like structures whose release is predominantly mediated by reactive oxygen species (ROS); their purpose is to combat infections. However, unbalanced NET production and clearance is involved in tissue injury, circulation of auto-an...

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Detalles Bibliográficos
Autores principales: Chicca, Ilaria J., Milward, Michael R., Chapple, Iain Leslie C., Griffiths, Gareth, Benson, Rod, Dietrich, Thomas, Cooper, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844942/
https://www.ncbi.nlm.nih.gov/pubmed/29556228
http://dx.doi.org/10.3389/fimmu.2018.00337