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Development and Application of High-Content Biological Screening for Modulators of NET Production
Neutrophil extracellular traps (NETs) are DNA-based antimicrobial web-like structures whose release is predominantly mediated by reactive oxygen species (ROS); their purpose is to combat infections. However, unbalanced NET production and clearance is involved in tissue injury, circulation of auto-an...
Autores principales: | Chicca, Ilaria J., Milward, Michael R., Chapple, Iain Leslie C., Griffiths, Gareth, Benson, Rod, Dietrich, Thomas, Cooper, Paul R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844942/ https://www.ncbi.nlm.nih.gov/pubmed/29556228 http://dx.doi.org/10.3389/fimmu.2018.00337 |
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