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Recipient rs1045642 Polymorphism Is Associated With Office Blood Pressure at 1-Year Post Kidney Transplantation: A Single Center Pharmacogenetic Cohort Pilot Study

Background: Corticosteroids are associated with reduced bone mineral density (BMD), as well as water and salt retention, leading to hypertension. They are substrates for P-glycoprotein, a protein coded by the highly polymorphic ABCB1 gene. We hypothesized that one ABCB1 polymorphism, rs1045642, is a...

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Detalles Bibliográficos
Autores principales: Bouatou, Yassine, Stenz, Ludwig, Ponte, Belen, Ferrari, Serge, Paoloni-Giacobino, Ariane, Hadaya, Karine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844966/
https://www.ncbi.nlm.nih.gov/pubmed/29556197
http://dx.doi.org/10.3389/fphar.2018.00184