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Apolipoprotein E-Mimetic Peptide COG1410 Promotes Autophagy by Phosphorylating GSK-3β in Early Brain Injury Following Experimental Subarachnoid Hemorrhage

COG1410, a mimetic peptide derived from the apolipoprotein E (apoE) receptor binding region, exerts positive effect on neurological deficits in early brain injury (EBI) after experimental subarachnoid hemorrhage (SAH). Currently the neuroprotective effect of COG1410 includes inhibiting BBB disruptio...

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Detalles Bibliográficos
Autores principales: Li, Xinshen, Peng, Jianhua, Pang, Jinwei, Wu, Yue, Huang, Xueping, Li, Yong, Zhou, Jian, Gu, Long, Sun, Xiaochuan, Chen, Ligang, Vitek, Michael P., Jiang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844970/
https://www.ncbi.nlm.nih.gov/pubmed/29556174
http://dx.doi.org/10.3389/fnins.2018.00127