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Carbapenem-Resistant Klebsiella pneumoniae Exhibiting Clinically Undetected Colistin Heteroresistance Leads to Treatment Failure in a Murine Model of Infection

Antibiotic resistance is a growing crisis and a grave threat to human health. It is projected that antibiotic-resistant infections will lead to 10 million annual deaths worldwide by the year 2050. Among the most significant threats are carbapenem-resistant Enterobacteriaceae (CRE), including carbape...

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Detalles Bibliográficos
Autores principales: Band, Victor I., Satola, Sarah W., Burd, Eileen M., Farley, Monica M., Jacob, Jesse T., Weiss, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844991/
https://www.ncbi.nlm.nih.gov/pubmed/29511071
http://dx.doi.org/10.1128/mBio.02448-17