Purkinje cell BKchannel ablation induces abnormal rhythm in deep cerebellar nuclei and prevents LTD

Purkinje cells (PC) control deep cerebellar nuclei (DCN), which in turn inhibit inferior olive nucleus, closing a positive feedback loop via climbing fibers. PC highly express potassium BK channels but their contribution to the olivo-cerebellar loop is not clear. Using multiple-unit recordings in al...

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Detalles Bibliográficos
Autores principales: Cheron, Guy, Márquez-Ruiz, Javier, Cheron, Julian, Prigogine, Cynthia, Ammann, Claudia, Lukowski, Robert, Ruth, Peter, Dan, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845018/
https://www.ncbi.nlm.nih.gov/pubmed/29523816
http://dx.doi.org/10.1038/s41598-018-22654-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845018/
https://www.ncbi.nlm.nih.gov/pubmed/29523816
http://dx.doi.org/10.1038/s41598-018-22654-6

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