gPKPDSim: a SimBiology(®)-based GUI application for PKPD modeling in drug development

Modeling and simulation (M&S) is increasingly used in drug development to characterize pharmacokinetic-pharmacodynamic (PKPD) relationships and support various efforts such as target feasibility assessment, molecule selection, human PK projection, and preclinical and clinical dose and schedule d...

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Detalles Bibliográficos
Autores principales: Hosseini, Iraj, Gajjala, Anita, Bumbaca Yadav, Daniela, Sukumaran, Siddharth, Ramanujan, Saroja, Paxson, Ricardo, Gadkar, Kapil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845055/
https://www.ncbi.nlm.nih.gov/pubmed/29302838
http://dx.doi.org/10.1007/s10928-017-9562-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845055/
https://www.ncbi.nlm.nih.gov/pubmed/29302838
http://dx.doi.org/10.1007/s10928-017-9562-9

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