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gPKPDSim: a SimBiology(®)-based GUI application for PKPD modeling in drug development
Modeling and simulation (M&S) is increasingly used in drug development to characterize pharmacokinetic-pharmacodynamic (PKPD) relationships and support various efforts such as target feasibility assessment, molecule selection, human PK projection, and preclinical and clinical dose and schedule d...
Autores principales: | Hosseini, Iraj, Gajjala, Anita, Bumbaca Yadav, Daniela, Sukumaran, Siddharth, Ramanujan, Saroja, Paxson, Ricardo, Gadkar, Kapil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845055/ https://www.ncbi.nlm.nih.gov/pubmed/29302838 http://dx.doi.org/10.1007/s10928-017-9562-9 |
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