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Predominant envelope variable loop 2-specific and gp120-specific antibody-dependent cellular cytotoxicity antibody responses in acutely SIV-infected African green monkeys

BACKGROUND: The initial envelope (Env)-specific antibody response in acutely HIV-1-infected individuals and simian immunodeficiency virus (SIV)-infected rhesus monkeys (RMs) is dominated by non-neutralizing antibodies targeting Env gp41. In contrast, natural primate SIV hosts, such as African green...

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Detalles Bibliográficos
Autores principales: Nguyen, Quang N., Martinez, David R., Himes, Jonathon E., Whitney Edwards, R., Han, Qifeng, Kumar, Amit, Mangan, Riley, Nicely, Nathan I., Xie, Guanhua, Vandergrift, Nathan, Shen, Xiaoying, Pollara, Justin, Permar, Sallie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845189/
https://www.ncbi.nlm.nih.gov/pubmed/29523166
http://dx.doi.org/10.1186/s12977-018-0406-5