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3C and 3C-based techniques: the powerful tools for spatial genome organization deciphering
It is well known that the chromosomes are organized in the nucleus and this spatial arrangement of genome play a crucial role in gene regulation and genome stability. Different techniques have been developed and applied to uncover the intrinsic mechanism of genome architecture, especially the chromo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845197/ https://www.ncbi.nlm.nih.gov/pubmed/29541161 http://dx.doi.org/10.1186/s13039-018-0368-2 |