Lipid accelerating the fibril of islet amyloid polypeptide aggravated the pancreatic islet injury in vitro and in vivo

BACKGROUND: The fibrillation of islet amyloid polypeptide (IAPP) triggered the amyloid deposition, then enhanced the loss of the pancreatic islet mass. However, it is not clear what factor is the determinant in development of the fibril formation. The aim of this study is to investigate the effects...

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Detalles Bibliográficos
Autores principales: Mo, Xiao-Dan, Gao, Li-Ping, Wang, Qing-Jun, Yin, Jie, Jing, Yu-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845206/
https://www.ncbi.nlm.nih.gov/pubmed/29523142
http://dx.doi.org/10.1186/s12944-018-0694-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845206/
https://www.ncbi.nlm.nih.gov/pubmed/29523142
http://dx.doi.org/10.1186/s12944-018-0694-8

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