C-Myc-dependent repression of two oncogenic miRNA clusters contributes to triptolide-induced cell death in hepatocellular carcinoma cells

BACKGROUND: Triptolide is a structurally unique diterpene triepoxide with potent antitumor activity. However,the effect and mechanism of triptolide on hepatocellular carcinoma (HCC) is not well studied. METHODS: Cells were treated with triptolide, and the anti-HCC activity of triptolide was evaluate...

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Detalles Bibliográficos
Autores principales: Li, Shu-Guang, Shi, Qian-Wei, Yuan, Ling-yan, Qin, Li-ping, Wang, Yan, Miao, Yu-Qing, Chen, Zhe, Ling, Chang-Quan, Qin, Wen-xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845216/
https://www.ncbi.nlm.nih.gov/pubmed/29523159
http://dx.doi.org/10.1186/s13046-018-0698-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845216/
https://www.ncbi.nlm.nih.gov/pubmed/29523159
http://dx.doi.org/10.1186/s13046-018-0698-2

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