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Highly efficient and expedited hepatic differentiation from human pluripotent stem cells by pure small-molecule cocktails

BACKGROUND: The advent of human-induced pluripotent stem cells holds great promise for producing ample individualized hepatocytes. Although previous efforts have succeeded in generating hepatocytes from human pluripotent stem cells in vitro by viral-based expression of transcription factors and/or a...

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Detalles Bibliográficos
Autores principales: Du, Cong, Feng, Yuan, Qiu, Dongbo, Xu, Yan, Pang, Mao, Cai, Nan, Xiang, Andy Peng, Zhang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845228/
https://www.ncbi.nlm.nih.gov/pubmed/29523187
http://dx.doi.org/10.1186/s13287-018-0794-4