Airway surface liquid from smokers promotes bacterial growth and biofilm formation via iron-lactoferrin imbalance

BACKGROUND: Smoking is a leading cause of respiratory infections worldwide. Tobacco particulate matter disrupts iron homeostasis in the lungs and increases the iron content in the airways of smokers. The airway epithelia secrete lactoferrin to quench iron required for bacteria to proliferate and cau...

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Detalles Bibliográficos
Autores principales: Vargas Buonfiglio, Luis G., Borcherding, Jennifer A., Frommelt, Mark, Parker, Gavin J., Duchman, Bryce, Vanegas Calderón, Oriana G., Fernandez-Ruiz, Ruth, Noriega, Julio E., Stone, Elizabeth A., Gerke, Alicia K., Zabner, Joseph, Comellas, Alejandro P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845328/
https://www.ncbi.nlm.nih.gov/pubmed/29524964
http://dx.doi.org/10.1186/s12931-018-0743-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845328/
https://www.ncbi.nlm.nih.gov/pubmed/29524964
http://dx.doi.org/10.1186/s12931-018-0743-x

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