Cargando…
Airway surface liquid from smokers promotes bacterial growth and biofilm formation via iron-lactoferrin imbalance
BACKGROUND: Smoking is a leading cause of respiratory infections worldwide. Tobacco particulate matter disrupts iron homeostasis in the lungs and increases the iron content in the airways of smokers. The airway epithelia secrete lactoferrin to quench iron required for bacteria to proliferate and cau...
Autores principales: | Vargas Buonfiglio, Luis G., Borcherding, Jennifer A., Frommelt, Mark, Parker, Gavin J., Duchman, Bryce, Vanegas Calderón, Oriana G., Fernandez-Ruiz, Ruth, Noriega, Julio E., Stone, Elizabeth A., Gerke, Alicia K., Zabner, Joseph, Comellas, Alejandro P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845328/ https://www.ncbi.nlm.nih.gov/pubmed/29524964 http://dx.doi.org/10.1186/s12931-018-0743-x |
Ejemplares similares
-
Effect of vitamin D(3) on the antimicrobial activity of human airway surface liquid: preliminary results of a randomised placebo-controlled double-blind trial
por: Vargas Buonfiglio, Luis G, et al.
Publicado: (2017) -
Effects of Coal Fly Ash Particulate Matter on the Antimicrobial Activity of Airway Surface Liquid
por: Vargas Buonfiglio, Luis G., et al.
Publicado: (2017) -
Seasonal Antimicrobial Activity of the Airway: Post-Hoc Analysis of a Randomized Placebo-Controlled Double-Blind Trial
por: Vargas Buonfiglio, Luis G., et al.
Publicado: (2020) -
Indoor Particulate Matter From Smoker Homes Induces Bacterial Growth, Biofilm Formation, and Impairs Airway Antimicrobial Activity. A Pilot Study
por: Stapleton, Emma M., et al.
Publicado: (2020) -
Mechanism of ambient particulate matter and respiratory infections
por: Vargas Buonfiglio, Luis G., et al.
Publicado: (2020)