S100A4 Protects Myeloid-Derived Suppressor Cells from Intrinsic Apoptosis via TLR4–ERK1/2 Signaling

Myeloid-derived suppressor cells (MDSCs) often expand during cancer or chronic inflammation and dampen immune responses. However, mechanisms underlying their capacity to escape intrinsic apoptosis in the inflammatory environment are still largely unknown. In this study, we investigated this in mouse...

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Detalles Bibliográficos
Autores principales: Li, Qingcui, Dai, Chengliang, Xue, Rui, Wang, Peigang, Chen, Lin, Han, Yijie, Erben, Ulrike, Qin, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845385/
https://www.ncbi.nlm.nih.gov/pubmed/29556233
http://dx.doi.org/10.3389/fimmu.2018.00388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845385/
https://www.ncbi.nlm.nih.gov/pubmed/29556233
http://dx.doi.org/10.3389/fimmu.2018.00388

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