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In Utero Administration of Drugs Targeting Microglia Improves the Neurodevelopmental Outcome Following Cytomegalovirus Infection of the Rat Fetal Brain

Congenital cytomegalovirus (CMV) infections represent one leading cause of neurodevelopmental disorders. Recently, we reported on a rat model of CMV infection of the developing brain in utero, characterized by early and prominent infection and alteration of microglia—the brain-resident mononuclear p...

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Detalles Bibliográficos
Autores principales: Cloarec, Robin, Bauer, Sylvian, Teissier, Natacha, Schaller, Fabienne, Luche, Hervé, Courtens, Sandra, Salmi, Manal, Pauly, Vanessa, Bois, Emilie, Pallesi-Pocachard, Emilie, Buhler, Emmanuelle, Michel, François J., Gressens, Pierre, Malissen, Marie, Stamminger, Thomas, Streblow, Daniel N., Bruneau, Nadine, Szepetowski, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845535/
https://www.ncbi.nlm.nih.gov/pubmed/29559892
http://dx.doi.org/10.3389/fncel.2018.00055