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Vortioxetine Treatment Reverses Subchronic PCP Treatment-Induced Cognitive Impairments: A Potential Role for Serotonin Receptor-Mediated Regulation of GABA Neurotransmission

Major depressive disorder (MDD) is associated with cognitive impairments that may contribute to poor functional outcomes. Clinical data suggests that the multimodal antidepressant vortioxetine attenuates some cognitive impairments in MDD patients, but the mechanistic basis for these improvements is...

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Detalles Bibliográficos
Autores principales: Pehrson, Alan L., Pedersen, Christian S., Tølbøl, Kirstine Sloth, Sanchez, Connie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845537/
https://www.ncbi.nlm.nih.gov/pubmed/29559911
http://dx.doi.org/10.3389/fphar.2018.00162