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Novel Approaches to Exploiting Invariant NKT Cells in Cancer Immunotherapy

iNKT cells are a subset of innate-like T cells that utilize an invariant TCR alpha chain complexed with a limited repertoire of TCR beta chains to recognize specific lipid antigens presented by CD1d molecules. Because iNKT cells have an invariant TCR, they can be easily identified and targeted in bo...

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Detalles Bibliográficos
Autores principales: Wolf, Benjamin J., Choi, Jiyoung Elizabeth, Exley, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845557/
https://www.ncbi.nlm.nih.gov/pubmed/29559971
http://dx.doi.org/10.3389/fimmu.2018.00384