Cargando…

Altered Function and Expression of ABC Transporters at the Blood–Brain Barrier and Increased Brain Distribution of Phenobarbital in Acute Liver Failure Mice

This study investigated alterations in the function and expression of P-glycoprotein (P-GP), breast cancer resistance protein (BCRP), and multidrug resistance-associated protein 2 (MRP2) at the blood–brain barrier (BBB) of acute liver failure (ALF) mice and its clinical significance. ALF mice were d...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Li, Miao, Mingxing, Chen, Yang, Wang, Zhongjian, Sun, Binbin, Liu, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845647/
https://www.ncbi.nlm.nih.gov/pubmed/29559914
http://dx.doi.org/10.3389/fphar.2018.00190