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Limitations and Challenges in Modeling Diseases Involving Spinal Motor Neuron Degeneration in Vitro

Pathogenic conditions involving degeneration of spinal motor neurons (MNs), such as amyotrophic lateral sclerosis, sarcopenia, and spinal cord injury, mostly occur in individuals whose spinal MNs are fully mature. There is currently no effective treatment to prevent death or promote axonal regenerat...

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Detalles Bibliográficos
Autores principales: Bucchia, Monica, Merwin, Samantha J., Re, Diane B., Kariya, Shingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845677/
https://www.ncbi.nlm.nih.gov/pubmed/29559895
http://dx.doi.org/10.3389/fncel.2018.00061