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Haem-iron plays a key role in the regulation of the Ess/type VII secretion system of Staphylococcus aureus RN6390

The Staphylococcus aureus type VII protein secretion system (T7SS) plays important roles in virulence and intra-species competition. Here we show that the T7SS in strain RN6390 is activated by supplementing the growth medium with haemoglobin, and its cofactor haemin (haem B). Transcript analysis and...

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Detalles Bibliográficos
Autores principales: Casabona, M. Guillermina, Kneuper, Holger, Alferes de Lima, Daniela, Harkins, Catriona P., Zoltner, Martin, Hjerde, Erik, Holden, Matthew T. G., Palmer, Tracy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845736/
https://www.ncbi.nlm.nih.gov/pubmed/29171824
http://dx.doi.org/10.1099/mic.0.000579