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Haem-iron plays a key role in the regulation of the Ess/type VII secretion system of Staphylococcus aureus RN6390
The Staphylococcus aureus type VII protein secretion system (T7SS) plays important roles in virulence and intra-species competition. Here we show that the T7SS in strain RN6390 is activated by supplementing the growth medium with haemoglobin, and its cofactor haemin (haem B). Transcript analysis and...
Autores principales: | Casabona, M. Guillermina, Kneuper, Holger, Alferes de Lima, Daniela, Harkins, Catriona P., Zoltner, Martin, Hjerde, Erik, Holden, Matthew T. G., Palmer, Tracy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845736/ https://www.ncbi.nlm.nih.gov/pubmed/29171824 http://dx.doi.org/10.1099/mic.0.000579 |
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