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TREK-1 Channel Expression in Smooth Muscle as a Target for Regulating Murine Intestinal Contractility: Therapeutic Implications for Motility Disorders

Gastrointestinal (GI) motility disorders such as irritable bowel syndrome (IBS) can occur when coordinated smooth muscle contractility is disrupted. Potassium (K(+)) channels regulate GI smooth muscle tone and are key to GI tract relaxation, but their molecular and functional phenotypes are poorly d...

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Detalles Bibliográficos
Autores principales: Ma, Ruolin, Seifi, Mohsen, Papanikolaou, Maria, Brown, James F., Swinny, Jerome D., Lewis, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845753/
https://www.ncbi.nlm.nih.gov/pubmed/29563879
http://dx.doi.org/10.3389/fphys.2018.00157