Caffeine Protects Dopaminergic Neurons From Dopamine-Induced Neurodegeneration via Synergistic Adenosine-Dopamine D2-Like Receptor Interactions in Transgenic Caenorhabditis elegans

Previous studies have suggested that caffeine reduces the risk of L-DOPA-induced dyskinesia. However, caffeine is also known to promote dopamine signaling, which seemingly contradicts this observed effect. To this end, the study aimed to clarify the mechanism of caffeine neuroprotection in vivo when...

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Detalles Bibliográficos
Autores principales: Manalo, Rafael V. M., Medina, Paul M. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845907/
https://www.ncbi.nlm.nih.gov/pubmed/29563862
http://dx.doi.org/10.3389/fnins.2018.00137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845907/
https://www.ncbi.nlm.nih.gov/pubmed/29563862
http://dx.doi.org/10.3389/fnins.2018.00137

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