High-efficiency transduction of spinal cord motor neurons by intrauterine delivery of integration-deficient lentiviral vectors

Integration-deficient lentiviral vectors (IDLVs) are promising gene delivery tools that retain the high transduction efficiency of standard lentiviral vectors, yet fail to integrate as proviruses and are instead converted into episomal circles. These episomes are metabolically stable and support lon...

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Detalles Bibliográficos
Autores principales: Ahmed, Sherif G., Waddington, Simon N., Boza-Morán, Maria Gabriela, Yáñez-Muñoz, Rafael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Publishers 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845930/
https://www.ncbi.nlm.nih.gov/pubmed/29289570
http://dx.doi.org/10.1016/j.jconrel.2017.12.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845930/
https://www.ncbi.nlm.nih.gov/pubmed/29289570
http://dx.doi.org/10.1016/j.jconrel.2017.12.029

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