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The hypoxia marker CAIX is prognostic in the UK phase III VorteX-Biobank cohort: an important resource for translational research in soft tissue sarcoma

BACKGROUND: Despite high metastasis rates, adjuvant/neoadjuvant systemic therapy for localised soft tissue sarcoma (STS) is not used routinely. Progress requires tailoring therapy to features of tumour biology, which need exploration in well-documented cohorts. Hypoxia has been linked to metastasis...

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Detalles Bibliográficos
Autores principales: Forker, Laura, Gaunt, Piers, Sioletic, Stefano, Shenjere, Patrick, Potter, Robert, Roberts, Darren, Irlam, Joely, Valentine, Helen, Hughes, David, Hughes, Ana, Billingham, Lucinda, Grimer, Rob, Seddon, Beatrice, Choudhury, Ananya, Robinson, Martin, West, Catharine M L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846059/
https://www.ncbi.nlm.nih.gov/pubmed/29235571
http://dx.doi.org/10.1038/bjc.2017.430