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The hypoxia marker CAIX is prognostic in the UK phase III VorteX-Biobank cohort: an important resource for translational research in soft tissue sarcoma
BACKGROUND: Despite high metastasis rates, adjuvant/neoadjuvant systemic therapy for localised soft tissue sarcoma (STS) is not used routinely. Progress requires tailoring therapy to features of tumour biology, which need exploration in well-documented cohorts. Hypoxia has been linked to metastasis...
Autores principales: | Forker, Laura, Gaunt, Piers, Sioletic, Stefano, Shenjere, Patrick, Potter, Robert, Roberts, Darren, Irlam, Joely, Valentine, Helen, Hughes, David, Hughes, Ana, Billingham, Lucinda, Grimer, Rob, Seddon, Beatrice, Choudhury, Ananya, Robinson, Martin, West, Catharine M L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846059/ https://www.ncbi.nlm.nih.gov/pubmed/29235571 http://dx.doi.org/10.1038/bjc.2017.430 |
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