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Human ex vivo prostate tissue model system identifies ING3 as an oncoprotein

BACKGROUND: Although the founding members of the INhibitor of Growth (ING) family of histone mark readers, ING1 and ING2, were defined as tumour suppressors in animal models, the role of other ING proteins in cellular proliferation and cancer progression is unclear. METHODS: We transduced ex vivo be...

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Detalles Bibliográficos
Autores principales: McClurg, Urszula L, Nabbi, Arash, Ricordel, Charles, Korolchuk, Svitlana, McCracken, Stuart, Heer, Rakesh, Wilson, Laura, Butler, Lisa M, Irving-Hooper, Bronwyn Kate, Pedeux, Rémy, Robson, Craig N, Riabowol, Karl T, Binda, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846061/
https://www.ncbi.nlm.nih.gov/pubmed/29381681
http://dx.doi.org/10.1038/bjc.2017.447